The efficacy and safety of Yadanzi oil injection in the treatment of advanced colon cancer
- Conditions
- advanced colon cancer
- Registration Number
- ITMCTR2100005321
- Lead Sponsor
- Shanxi Province Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Age 18-80, no gender limitation;
2. Patients with tumor whose clinical stage was stage IV and could not be radically resected.
3. No previous chemotherapy;
4. Quality of Life Score (KPS Score) =60;
5. The expected survival time is more than 6 months;
6. Good compliance; informed consent was signed before enrollment;
7. Patients agree not to participate in other intervention studies during treatment.
1. Those with specific targeted therapy through genetic testing;
2. Patients with other primary malignant tumors;
3. Patients with serious complications of cardiovascular system, cerebrovascular system, active hepatitis, and serious liver and kidney dysfunction that can't tolerate chemotherapy;
4. Patients with severe bleeding tendency who cannot use bevacizumab;
5. Those who have received first-line chemotherapy or above;
6. Patients receiving other immunotherapy;
7. Allergic to the test drug;
8. Women during lactation and pregnancy;
9. Those who cannot comply with the requirements of the scheme or experiment;
10. People with severe mental illness, bad fluid, and can't cooperate with treatment;
11. Used other Proprietary Chinese medicines with anti-tumor and improved immunity.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method DCR;PFS;
- Secondary Outcome Measures
Name Time Method immunologic function;quality of life;tumor marker;assessment of the safety;