Erector Spinae Plane Block Versus Retrolaminar Block for Analgesia in Percutaneous Nephrolithotomy

Not Applicable

Completed

• Conditions: Postoperative Analgesia; Pain Management; PCNL; Regional Anesthesia Block

• Registration Number: NCT06710444
• Lead Sponsor: Alexandria University

Brief Summary

The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia

Detailed Description

All the patients will be blinded to the intervention received in this study. All patients will receive standard general anesthesia technique with endotracheal intubation and muscle paralysis. Postoperatively, all patients will receive analgesia in the form of non-steroidal anti-inflammatory drugs and paracetamol. In case the VAS scores exceeded 4 in any group, the patients will receive rescue analgesia with 25 mg IV meperidine. In both groups, the ESPB and RLB will be performed after induction of general anesthesia using portable ultrasound device.

Study Timeline

• Study First Submitted: 2024-11-26
• Study First Submitted QC: 2024-11-27
• Study First Posted: 2024-11-29
• Study Start: 2024-12-01
• Primary Completion: 2025-03-01
• Study Completion: 2025-04-01
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-09
• Last Update Posted: 2025-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Patients scheduled for PCNL

Exclusion Criteria

• daily consumption of analgesics
• allergy to local anesthetics
• liver dysfunction
• infection or previous surgery in the vertebral region.
• patient refusal
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
measurement of visual analogue score	after the surgery average 48 hours postoperative	measurement of visual analogue score during rest and movement. The Score range from 0-10. 0 means no pain and 10 indicates the worst pain ever

Secondary Outcome Measures

Name	Time	Method
postoperative additional analgesic requirement	after the surgery average 48 hours postoperative	Total cumulative analgesic requirement dose
assessing the patient satisfaction by a the short assessment of patient satisfaction score (SAPS)	after the surgery average 48 hours postoperative	from 0 to 28, where 0 is so dissatisfied and 28 means very satisfied
Time to ambulate	after the surgery average 12 hours postoperative	Time from discharge from the operating theatre to start to ambulate
presence of postoperative nausea and vomiting	after the surgery average 48 hours postoperative	Number of postoperative nausea and vomiting

Trial Locations

Locations (1)

Ahmed S.Shehab; 🇪🇬 Alexandria, Egypt