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Clinical Trials/NCT06710444
NCT06710444
Completed
Not Applicable

Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy

Alexandria University1 site in 1 country120 target enrollmentDecember 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Analgesia
Sponsor
Alexandria University
Enrollment
120
Locations
1
Primary Endpoint
measurement of visual analogue score
Status
Completed
Last Updated
11 months ago

Overview

Brief Summary

The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia

Detailed Description

All the patients will be blinded to the intervention received in this study. All patients will receive standard general anesthesia technique with endotracheal intubation and muscle paralysis. Postoperatively, all patients will receive analgesia in the form of non-steroidal anti-inflammatory drugs and paracetamol. In case the VAS scores exceeded 4 in any group, the patients will receive rescue analgesia with 25 mg IV meperidine. In both groups, the ESPB and RLB will be performed after induction of general anesthesia using portable ultrasound device.

Registry
clinicaltrials.gov
Start Date
December 1, 2024
End Date
April 1, 2025
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Shehab, MD

Lecturer in Anaesthesia and Surgical ICU department

Alexandria University

Eligibility Criteria

Inclusion Criteria

  • Patients scheduled for PCNL

Exclusion Criteria

  • daily consumption of analgesics
  • allergy to local anesthetics
  • liver dysfunction
  • infection or previous surgery in the vertebral region.
  • patient refusal
  • pregnancy

Outcomes

Primary Outcomes

measurement of visual analogue score

Time Frame: after the surgery average 48 hours postoperative

measurement of visual analogue score during rest and movement. The Score range from 0-10. 0 means no pain and 10 indicates the worst pain ever

Secondary Outcomes

  • postoperative additional analgesic requirement(after the surgery average 48 hours postoperative)
  • assessing the patient satisfaction by a the short assessment of patient satisfaction score (SAPS)(after the surgery average 48 hours postoperative)
  • Time to ambulate(after the surgery average 12 hours postoperative)
  • presence of postoperative nausea and vomiting(after the surgery average 48 hours postoperative)

Study Sites (1)

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