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Clinical Trials/NCT05845788
NCT05845788
Completed
Not Applicable

Comparison of the Intraoperative and Postoperative Effects of Ultrasound-guided Erector Spina Plane Block and Posterior Quadratus Lumborum Block in Patients Undergoing Lumbar Stabilization Surgery

Ankara City Hospital Bilkent1 site in 1 country62 target enrollmentApril 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postprocedural Analgesia
Sponsor
Ankara City Hospital Bilkent
Enrollment
62
Locations
1
Primary Endpoint
İntraoperative remifentanil consumption
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The investigators aimed to compare the effects of ultrasound guided erector spina plan block and posterior quadratus lumborum block on intraoperative and postoperative opioid consumption in patients who will undergo short segment lumbar stabilization surgery.

Detailed Description

All participants will be monitored with ECG, SpO2, non-invasive blood pressure. In induction, 1mg/kg 2% lidocaine, 2-3mg/kg propofol, 1mcg/kg fentanyl, 2mg midazolam, 0.6 mg/kg rocuronium will be used. Anesthesia depth will be monitored with BIS (bispectral index), and anesthesia will be maintained with 50% oxygen-air mixture and sevoflurane. After patient intubation, invasive artery cannulation will be performed on the non-dominant hand, and the patients will be placed in a prone position. 20 cc bupivacaine of 0.25% will be administered to both regions bilaterally, by following the rules of asepsis, with a 10 cm pajunk needle accompanied by USG, the needle site will be confirmed with 3 mm saline. BIS will be kept in the range of 40-50 throughout the case, and invasive arterial monitoring will be performed. 1 g paracetamol, 1 mg/kg tramadol and 4 mg ondansetron will be administered to the patients 30 minutes before the end of the surgery. After appropriate extubation and wakefulness, patients will be transferred to the postoperative anesthesia care unit (PACU), where they will be followed for 24 hours. An intravenous (IV) patient-controlled analgesia device (PCA) containing 100ml of tramadol at a concentration of 4mg/cc will be inserted. No infusion will be given, and the bolus dose will be set to 20mg, with a lock time of 20 minutes. In the postoperative period, 50 mg of dexketoprofen will be administered every 8 hours. VAS values, vital signs, and possible opioid side effects of the patients at 0, 1, 2, 6, 12 and 24 hours will be recorded. After completing 24 hours, the patient will be separated from the IV PCA device and transferred to the service.

Registry
clinicaltrials.gov
Start Date
April 15, 2023
End Date
August 2, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nihal Gökbulut Özaslan

Principal Investigator

Ankara City Hospital Bilkent

Eligibility Criteria

Inclusion Criteria

  • Patients who will undergo lumbar stabilization operation
  • Between the ages of 18-65
  • Both genders
  • ASA I-III risk group

Exclusion Criteria

  • Patients who did not accept the study
  • Patients younger than 18 years old
  • Patients older than 65 years
  • Patients with an ASA score greater than III
  • Patients with an active infection in the area to be blocked
  • Patients with a long bleeding time
  • Those who are pregnant
  • Patients with kidney failure
  • Patients with liver failure
  • Patients with BMI\<18 and BMI\>30

Outcomes

Primary Outcomes

İntraoperative remifentanil consumption

Time Frame: At the end of the intraoperative period

The investigators aimed to compare intraoperative remifentanil consumption of two groups

Postoperative tramadol consumption

Time Frame: The investigators will record at postoperative 24. hour

The investigators aimed to compare postoperative tramadol consumption of two groups

Secondary Outcomes

  • Postoperative visual analog scale(The investigators will record at postoperative 24. hour)
  • Postoperative nausea and vomiting(The investigators will record within 24 hours postoperatively.)
  • Postoperative pruritus(The investigators will record within 24 hours postoperatively.)

Study Sites (1)

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