CytoSorb in Patients With Liver Failure

Completed

• Conditions: Liver Dysfunction
• Interventions: Procedure: hemoadsorption

• Registration Number: NCT04511507
• Lead Sponsor: Institutul Clinic Fundeni

Brief Summary

Hemoadsorption has been demonstrated to improve liver functional tests in patients with liver failure. The present study investigates the effects of three consecutive sessions of hemoadsorption, performed in accordance to the local protocol for treating patients with acute liver failure, on liver functional tests, severity scores and 30-days mortality. Paraclinical results and severity scores were obtained before and after the three consecutive sessions.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02-10
• Study First Submitted: 2020-08-11
• Study First Submitted QC: 2020-08-11
• Study First Posted: 2020-08-13
• Primary Completion: 2021-08-30
• Study Completion: 2021-08-30
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-03
• Last Update Posted: 2021-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• patients with acute liver failure or acute on chronic liver failure who require hemoadsorption in accordance with local guidelines

Exclusion Criteria

• unsigned informed consent
• duration of therapy under 12 hours
• death before the three consecutive sessions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
liver failure	hemoadsorption	patients diagnosed with acute liver failure or acute on chronic liver failure in accordance with national guidelines who require 3 consecutive sessions of hemoadsorption

Primary Outcome Measures

Name	Time	Method
30 days mortality	30 days	30 days mortality

Trial Locations

Locations (1)

Fundeni Clinical Institute; 🇷🇴 Bucharest, Romania