Biomarker study of folate receptor alpha(FOLRa)using paired samples of breast cancer tissue
Not Applicable
Recruiting
- Conditions
- Breast cancer
- Registration Number
- JPRN-UMIN000050787
- Lead Sponsor
- Showa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1.Not undergoing systemic therapy 2.Patients deemed unsuitable by a physician for other reasons
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of the patients with FOLRa-positive breast cancer
- Secondary Outcome Measures
Name Time Method Proportions of cases with increased, unchanged, or decreased IHC scores for FOLRa in paired samples (primary vs. metastatic, pre- vs. post-treatment) Correlation of FOLRa scores in cell membrane, cytoplasm, and cell membrane + cytoplasm Association between FOLRa expression and ER/PgR positivity, Ki-67 index, and PD-L1 positivity Relationship between treatment regimen and changes in FOLRa expression levels