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Multimodal Postoperative Analgesia Following OSA Surgery

Not Applicable
Conditions
Obstructive Sleep Apnea
Interventions
Combination Product: Nalbuphine, ketorolac, accufuser
Registration Number
NCT04483427
Lead Sponsor
Bahaa Mohammed Refaie
Brief Summary

Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia following multilevel OSA surgeries

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • physical status of American Society of Anesthesiologists (ASA) II
  • age between 30 - 50 years
  • OSA patients diagnosed by polysomnography and stop-bang questionnaire
  • enrolled for multilevel OSA surgery
Exclusion Criteria
  • history of allergy to the study drugs
  • history of hepatic, cardiopulmonary or renal disease
  • history of any chronic pain on medication
  • history of substance abuse
  • psychiatric disorder
  • lack of patient cooperation.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
OSA patients after multilevel surgeryNalbuphine, ketorolac, accufuser-
Primary Outcome Measures
NameTimeMethod
Postoperative painAssessment will be carried out 48 hours postoperatively

Visual analog pain score

Secondary Outcome Measures
NameTimeMethod
Sedation level48 hours postoperatively

Ramsey Sedation Ramsey Sedation Scale

incidence of adverse effects48 hours postoperatively

hypoxia, nausea, vomiting, itching

Trial Locations

Locations (1)

Sohag faculty of medicine

🇪🇬

Sohag, Egypt

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