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OrthoCarolina Research Institute, Inc.

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 2006-01-01

Employees: 11

Market Cap: -

Website: https://orthocarolinaresearch.org

Clinical Trials

Prophylactic TBR on Phantom Limb Pain

Not Applicable

Not yet recruiting

Conditions: Phantom Limb Pain After Amputation

First Posted Date: 2025-05-04

Last Posted Date: 2025-05-04

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 50

Registration Number: NCT06956508

Locations: 🇺🇸
OrthoCarolina Research Institute, Charlotte, North Carolina, United States

Prospective Opioid-Free AIS Fusion

Phase 4

Not yet recruiting

Conditions: Adolescent Idiopathic Scoliosis (AIS)

Interventions: Drug: Opioid-Containing
Drug: Opioid-Free/Opioid-Avoidant

First Posted Date: 2025-04-20

Last Posted Date: 2025-04-20

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 58

Registration Number: NCT06935331

Locations: 🇺🇸
OrthoCarolina Research Institute, Charlotte, North Carolina, United States

Intra-Articular Catheter Total Knee Arthroplasty

Phase 4

Conditions: Continuous Local Infiltration Analgesia
Intra-articular Catheter
Total Knee Arthroplasty

Interventions: Other: Routine Standard of Care Treatment
Device: Intra-articular catheter

First Posted Date: 2024-08-30

Last Posted Date: 2025-03-20

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 65

Registration Number: NCT06580899

Locations: 🇺🇸
OrthoCarolina Research Institute, Inc., Charlotte, North Carolina, United States

Tourniquet Use in Anterior Cruciate Ligament Repair

Not Applicable

Conditions: ACL Tear
ACL - Anterior Cruciate Ligament Deficiency
ACL Injury

Interventions: Procedure: Patients undergoing ACL reconstruction with or without a tourniquet

First Posted Date: 2023-07-05

Last Posted Date: 2025-04-30

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 34

Registration Number: NCT05931627

Locations: 🇺🇸
OrthoCarolina Research Institute, Inc., Charlotte, North Carolina, United States

Cemented vs. Cementless TKA

Not Applicable

Terminated

Conditions: Total Knee Arthroplasty (TKA)

Interventions: Procedure: Cementless Total Knee Arthroplasty
Procedure: Cemented Total Knee Arthroplasty

First Posted Date: 2020-10-22

Last Posted Date: 2022-04-08

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 17

Registration Number: NCT04597684

Locations: 🇺🇸
OrthoCarolina Research Institute, Charlotte, North Carolina, United States

Adductor Canal Block

Phase 2

Active, not recruiting

Conditions: Total Knee Replacement
Osteoarthritis

Interventions: Drug: Saline Injection
Drug: Ropivacaine injection
Procedure: Total Knee Arthroplasty

First Posted Date: 2020-08-14

Last Posted Date: 2025-04-28

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 130

Registration Number: NCT04513145

Locations: 🇺🇸
OrthoCarolina Research Institute, OrthoCarolina, P.A., Charlotte, North Carolina, United States

Opioid-Free Orthopaedic Surgery

Not Applicable

Completed

Conditions: Pain Management

Interventions: Drug: Opioids
Drug: Opioid-Free

First Posted Date: 2019-11-25

Last Posted Date: 2025-03-20

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 511

Registration Number: NCT04176783

Locations: 🇺🇸
OrthoCarolina, P.A., Charlotte, North Carolina, United States

Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?

Phase 4

Conditions: Joint Infection

Interventions: Drug: Intraoperative Intraosseous Vancomycin

First Posted Date: 2018-10-19

Last Posted Date: 2025-03-20

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 100

Registration Number: NCT03713528

Locations: 🇺🇸
University of California, San Francisco, San Francisco, California, United States
🇺🇸
University of Florida, Gainesville, Florida, United States
🇺🇸
Cleveland Clinic Florida, Weston, Florida, United States

and more 7 locations

Opioid-Free Shoulder Arthroplasty

Phase 4

Completed

Conditions: Arthritis;Inflammatory
Opioid Use
Shoulder Osteoarthritis
Avascular Necrosis
Rotator Cuff Tear

Interventions: Drug: Gabapentin
Drug: Celecoxib
Drug: toradol
Drug: acetaminophen
Drug: regional block
Drug: propofol
Drug: IV lidocaine
Drug: rocuronium
Drug: vecuronium
Drug: sevoflurane
Drug: desflurane

First Posted Date: 2018-05-30

Last Posted Date: 2020-10-14

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 86

Registration Number: NCT03540030

Locations: 🇺🇸
OrthoCarolina Research Institute, Charlotte, North Carolina, United States

Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint

Not Applicable

Completed

Conditions: Anterior Cruciate Ligament Reconstruction

Interventions: Procedure: Anterior Cruciate Ligament Reconstruction

First Posted Date: 2016-06-10

Last Posted Date: 2024-04-02

Lead Sponsor: OrthoCarolina Research Institute, Inc.

Target Recruit Count: 30

Registration Number: NCT02795247

Locations: 🇺🇸
OrthoCarolina Sports Center, Charlotte, North Carolina, United States

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