Influence of a 3 weeks cardiological rehabilitation on advanced glycation endproducts respectively their receptor

• Conditions: I25; Chronic ischaemic heart disease

• Registration Number: DRKS00010509
• Lead Sponsor: udwig Boltzmann Gesellschaft

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06-02
• Study Completion: 2017-04-26
• Results First Posted: 2023-02-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

age from 25 to 75 years, coronary heart disease (stadium post myocardial infarction, stadium post percutaneous translumal coronary angioplasty, stadium post Coronary Artery Bypass Graft)

Exclusion Criteria

kidney insufficiency from state III (creatininclearance beyond 60 ml/min after Cockcroft-Galut); acute inflammatory disease (CRP cut off > 1,0 mg/dl); operation or bigger trauma bevor < 6 weeks; myocardial infarction < 6 weeks ago

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of AGEs (Advanced Glycation Endproducts) in the course of a 3-weeks in-patient rehabilitation stay (determination of anthropometry, anamnesis and AGE-levels in the skin with AGE-reader at admission and discharge)

Secondary Outcome Measures

Name	Time	Method
Improvement of sRAGE and peroxides in the course of a 3-weeks in-patient rehabilitation stay (determination from serum with ELISA-kits, serum is taken at admission and discharge)