EUCTR2014-003680-38-NL进行中（未招募）不适用
Pharmacokinetics of two different high dose regimes of intravenous vitamin C in critically ill patients - Pharmacokinetics of two different high dose regimes of intravenous vitamin C in critically ill patie
VU university medical center0 个研究点开始时间: 2015年3月4日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Sepsis or SIRS (systemic inflammatory response syndrome), after major surgery or trauma
- •Non-neurological sequential organ failure score >6
- •Expected length of ICU stay > 96 hours
- •Informed consent by patient or legal representative
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 10
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 10
排除标准
- •Admission after out of hospital cardiac arrest
- •Prior use of supplemental vitamin C in the week before
- •Major bleeding
- •Pre-existent renal insufficiency defined as an eGFR of < 30 ml/min/1.73 m2 (stadium 4-5)
- •Expected need for renal replacement therapy within 48 hours
- •Known glucose 6-phosphate dehydrogenase deficiency
- •History of urolithiasis or oxalate nephropathy
- •Previous use of prolonged high dose vitamin C supplements
- •Hemochromatosis
研究者
相似试验
已完成
4 期
Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill PatientsMultiple Organ FailureTraumaSepsisSystemic Inflammatory Response SyndromeNCT02455180Amsterdam UMC, location VUmc20
已完成
2 期
Pharmacokinetics of two high dose regimes of intravenous vitamin C in critically ill patientssepsissepsis of SIRS (systemische inflammatie) met orgaanfalentraumaNL-OMON42302Vrije Universiteit Medisch Centrum20
尚未招募
3 期
Investigating the effect of vitamin D in the treatment of diabetic foot ulcersDiabetic foot ulcer.Diabetes mellitus due to underlying condition with diabetic neuropathic arthropathyE08.610IRCT20220928056051N4Oroumia University of Medical Sciences60
尚未招募
不适用
A study to compare two different dose-combinations of Propofol(Induction agent)and Ketamine(Induction agent)(Ketofol) as induction agent for patients undergoing surgery under general anaesthesia.CTRI/2020/06/025990Government Mohan Kumaramangalam Medical College and Hospital
已完成
3 期
Assessment the therapeutic effect of pantoprazole in patients with gastrointestinal bleedingpper gastro intestinal bleeding.Diseases of oesophagus, stomach and duodenumk20-k31IRCT201202289160N1Research Deputy of Ahvaz University of Medical Sciences166