ACTRN12613000059763
Not yet recruiting
未知
The role of FTO Gene Variants on Metabolic Flexibility and Training Adaptations in Relatively Healthy Males following a 12 Week High Intensity Exercise Intervention
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Metabolic Flexibility
- Sponsor
- Victoria University
- Enrollment
- 20
- Status
- Not yet recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Participants will be considered relatively healthy males with the FTO rs9939609 risk allele (A) or two FTO rs9939609 wild type alleles (TT). Participants will be included if they have adequate glucose handling (no diagnosed diabetes, fasting blood glucose must be less than 7\.0 mmol/L), not performing any regular fitness training (i.e. greater than 30 minutes, 3 times per week) for the past 6 months, not taking contraindicated prescription medication (i.e. thyroid, hyperlipidmeic, hypoglycemic, or antihypertensive), do have physician approval (if BMI over 25kg.m\-2\), and not current involvement in other research studies.
Exclusion Criteria
- •Participants will be excluded from participating within the project for the following reasons: diagnosed diabetes (fasting blood glucose greater than 7\.0 mmol/L or HbA1ctest greater than 6\.5%), performing any regular fitness training (i.e. greater than 30 minutes, 3 times per week) for the past 6 months, taking contraindicated prescription medication (i.e. thyroid, hyperlipidmeic, hypoglycemic, or antihypertensive), no physician approval (if BMI over 25kg.m\-2\), and current involvement in other research studies.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-DietObesityInsulin ResistanceDyslipidemiasAdvance GlycationInflammationNCT06426017Khyber Medical University Peshawar110
Completed
Not Applicable
FTO Gene Variants and Diet in ObesityObesityDiet HabitGenetic PredispositionNCT04205318Hacettepe University400
Recruiting
Not Applicable
Effect of the FTO-genotypes on the differences in energy expenditure after cold exposureThe FREECE studyhealthy subjectsDRKS00010489ehrstuhl für ErnährungsmedizinZIEL ErnährungsmedizinTU München120
Completed
Not Applicable
A study examining the importance of genetic variation for the ability of severely ill anorectic women to gain weight during three yearsAnorexia nervosaMental and Behavioural DisordersISRCTN76310580Sahlgrenska University Hospital25
Completed
Phase 2
FTO-genotype dependent weight reduction under treatment with bromocriptine in obese patientsadipositasE66.0Obesity due to excess caloriesDRKS00003349niversität zu Köln47