Metabolic Response to Food in Lung Cancer
Active, not recruiting
- Conditions
- Carcinoma, Non-Small-Cell Lung
- Registration Number
- NCT05937074
- Lead Sponsor
- Pennington Biomedical Research Center
- Brief Summary
This goal of this study is to describe how unintentional weight loss influences fasting and post-prandial metabolic flexibility in participants with advanced non-small cell lung cancer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
- Age greater than or equal to 18 years
- Diagnosis of non-small-cell lung cancer
- Reported weight stability or loss after cancer diagnosis
- Body mass index less than or equal to 35 kilograms per meter squared
- Ability to provide written informed consent
- Willing and able to comply with all scheduled visits, treatment plans, lab tests, and other study procedure
- Allow the collection and storage of biospecimens and data for future use
Exclusion Criteria
- Prior diagnosis of diabetes mellitus (type 1 or type 2)
- Currently pregnant or breastfeeding
- Contraindication to consuming the liquid mixed meal
- Any medications affecting gastric motility
- Any other condition that, in the investigator's opinion, would preclude participation or successful compliance with the protocol
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory quotient Difference between pre- to post-prandial conditions over four hours The respiratory quotient will be measured by indirect calorimetry before and after consumption of a liquid mixed meal
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Pennington Biomedical Research Center
🇺🇸Baton Rouge, Louisiana, United States
Pennington Biomedical Research Center🇺🇸Baton Rouge, Louisiana, United States