Pre-hOspital evaluation of chest Pain patients with sUspected non ST-segment eLevation myocARdial infarction using the HEART-score with a Troponin point-of-care test

Completed

Conditions: acute coronary syndrome
chest pain
10082206

Registration Number: NL-OMON49607

Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 650

Inclusion Criteria

- All out-of-hospital chest pain patients visited by an ambulance
- Transportation to a hospital with working diagnosis non ST-segment elevation
acute coronary syndrome
- Age >= 18 years

Exclusion Criteria

• Comatose state
• Cognitive impairment
• Pregnancy
• Hemodynamic instability or shock
• No pre-hospital 12-lead ECG performed or available
• Electrocardiographic ST-segment elevation in the prehospital phase
• An obvious non-cardiac cause for the chest complaints (trauma, pneumothorax,
pneumonia, etc.)
• Suspicion of aortic dissection or pulmonary embolism

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints:<br /><br>1. HEART-score agreement (interobserver variability between pre-hospital and<br /><br>in-hospital HEART-score assessment) (primary objective)<br /><br>2. Final diagnosis of NSTE-ACS at discharge<br /><br>3. Myocardial infarction at discharge</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters/endpoints:<br /><br>4. Composite endpoint (cardiovascular mortality, myocardial infarction, urgent<br /><br>revascularisation) at 30 days<br /><br>5. Angina frequency and stability, physical limitations, treatment<br /><br>satisfaction, quality-of-life, cardiac anxiety and depression (SAQ, PHQ-4)</p><br>