Fast Assessment and Management of Chest Pain without ST-elevation in the Pre-hospital Gateway;The implementation phase

Completed

Conditions: Chest pain
NSTEMI
10011082

Registration Number: NL-OMON45480

Lead Sponsor: Isala Klinieken

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 545

Inclusion Criteria

Chest pain persons without ST segment elevation that are visited by an ambulance

Exclusion Criteria

- Comatose state
- Cognitive impairment
- Pregnancy
- Shock
- Cardiac asthma
- Sustained ventricular tachyarrhythmia
- Electrocardiographic ST-segment elevation
- Endstage renal disease
- No pre-hospital 12-lead ECG performed or available
- An obvious non-cardiac cause for chest complaints (trauma, pneumothorax, pneumonia, etc.)
- Strong suspicion of aortic dissection or pulmonary embolism

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is the occurrence of MACE at 6 weeks of inclusion in the<br /><br>total group. MACE includes: myocardial infarction, PCI, CABG, death by all<br /><br>causes. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- The occurrence of MACE at 6 months of inclusion.<br /><br>- Number of patients that are secondarily referred to the hospital with a HEART<br /><br>score of <=3 at 6 weeks and 6 months after inclusion.<br /><br>- Discharge diagnosis of all patient primarily or secondarily referred to the<br /><br>hospital within 6 months after inclusion.<br /><br>- Health care costs.<br /><br>- The number of inter-hospital transfers between PCI and non-PCI centres in<br /><br>intermediate and high risk patient groups.<br /><br>- Length of hospital stay.<br /><br>- Performed diagnostics.<br /><br>- Cause of death.<br /><br>- Differences in patient characteristics between the low, intermediate and high<br /><br>risk groups.<br /><br>- Quality of life obtained with SF36 questionnaire at 6 months.</p><br>