Geriatric Intervention in Elderly Surgical Patients With Colorectal Cancer - a Randomized, Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 122
- 试验地点
- 2
- 主要终点
- Postoperative complications
研究概览
简要总结
This is a randomized, controlled trial on frail elderly patients (aged 65+) with colorectal cancer. The patients will be randomized into two groups. The control group will receive standard surgical treatment. The intervention group will in addition go through a preoperative comprehensive geriatric assessment. The assessment will include evaluation of co-morbidity and medication, social status, nutritional status, cognition, depression and physical performance. This assessment will form basis of an individualized perioperative intervention.
The main aim of the study is to see if the number of postoperative complications in this group can be reduced by a perioperative geriatric intervention. A study of inflammation markers in serum will also be performed, with focus on identifying potential biological frailty markers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective surgery for colorectal cancer
排除标准
- •Acute surgery
- •Not able to consent
- •Does not consent with registration
结局指标
主要结局
Postoperative complications
时间窗: 30 days after surgery
次要结局
- Readmission(30 days after surgery)
- Living at home or in institution(3 months after surgery)
- Length of hospital stay(30 days after surgery)
- Survival(3 months after surgery)
- Reoperation(30 days after surgery)
- Quality of life(3 months after surgery)
研究者
Torgeir Bruun Wyller
Professor
Oslo University Hospital