A Comparative Study Of Equipotent Doses Of Intrathecal Levobupivacaine With Fentanyl And Ropivacaine With Fentanyl For Lower Abdominal And Lower Extremity Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Levobupivacaine + Fentanyl group-
研究概览
简要总结
We conducted a randomized Comparative study in 60 ASA 1 patients undergoing lower Abdominal or lower Extremity surgery, divided into 2 groups 30 of each, LF and RF. Group LF was given Intrathecal Levobupivacaine 15mg+ Fentanyl 25mcg. Group RF was given Intrathecal Ropivacaine 22.5mg+ Fentanyl 25mcg. We compared the onset and duration of sensory block as well as motor block, duration of analgesia, hemodynamic stability and side effects. We found that Levobupivacaine had faster onset as well as longer duration of both sensory and motor block and longer duration of analgesia also with comparable hemodynamics. So we recommend the use of Intrathecal Levobupivacaine combined with Fentanyl for lower Abdominal And Lower Extremity surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA CLASS 1 OR 2 Duration of surgery < 120minutes Body weight 30 to 80 kg.
排除标准
- •ASA CLASS 3 OR 4 Emergency surgery Pregnancy Contraindications to subarachnoid block.
结局指标
主要结局
Levobupivacaine + Fentanyl group-
时间窗: For Onset 30min | For Duration 360min
Onset of sensory block was 2.9 min
时间窗: For Onset 30min | For Duration 360min
Onset of motor block was 3mins
时间窗: For Onset 30min | For Duration 360min
Duration of sensory block was 271.5 mins
时间窗: For Onset 30min | For Duration 360min
Duration of motor block was 252.1 mins
时间窗: For Onset 30min | For Duration 360min
Ropivacaine + Fentanyl group-
时间窗: For Onset 30min | For Duration 360min
Onset of sensory block was 3.9mins
时间窗: For Onset 30min | For Duration 360min
Onset of motor block was 5mins
时间窗: For Onset 30min | For Duration 360min
Duration of sensory block was 228 mins
时间窗: For Onset 30min | For Duration 360min
Duration of motor block was 195.3 mins
时间窗: For Onset 30min | For Duration 360min
次要结局
- Duration of analgesia-(Levobupivacaine group 292.8mins)