Comparation of spinal Levobupivacaine With Fentanyl And Ropivacaine With Fentanyl For Lower Abdominal And Lower Limb Surgery

Phase 4

Completed

• Conditions: Scheduled for lower Abdominal And Lower Extremity surgeries

• Registration Number: CTRI/2018/05/014012
• Lead Sponsor: St Stephens hospital

Brief Summary

We conducted a randomized Comparative study in 60 ASA 1 patients undergoing lower Abdominal  or lower Extremity surgery, divided into 2 groups 30 of each, LF and RF. Group LF was given Intrathecal Levobupivacaine 15mg+ Fentanyl 25mcg. Group RF was given Intrathecal Ropivacaine 22.5mg+ Fentanyl 25mcg. We compared the onset and duration of sensory block as well as motor block, duration of analgesia, hemodynamic stability and side effects. We found that Levobupivacaine had faster onset as well as longer duration of both sensory and motor block and longer duration of analgesia also with comparable hemodynamics. So we recommend the use of Intrathecal Levobupivacaine combined with Fentanyl for lower Abdominal And Lower Extremity surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-01
• Study Completion: 2015-06-25
• Last Update Posted: 2018-05-15

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA CLASS 1 OR 2 Duration of surgery < 120minutes Body weight 30 to 80 kg.

Exclusion Criteria

ASA CLASS 3 OR 4 Emergency surgery Pregnancy Contraindications to subarachnoid block.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset of sensory block was 2.9 min	For Onset 30min | For Duration 360min
Onset of motor block was 3mins	For Onset 30min | For Duration 360min
Duration of sensory block was 271.5 mins	For Onset 30min | For Duration 360min
Duration of motor block was 252.1 mins	For Onset 30min | For Duration 360min
Ropivacaine + Fentanyl group-	For Onset 30min | For Duration 360min
Onset of sensory block was 3.9mins	For Onset 30min | For Duration 360min
Onset of motor block was 5mins	For Onset 30min | For Duration 360min
Duration of sensory block was 228 mins	For Onset 30min | For Duration 360min
Duration of motor block was 195.3 mins	For Onset 30min | For Duration 360min
Levobupivacaine + Fentanyl group-	For Onset 30min | For Duration 360min

Secondary Outcome Measures

Name	Time	Method
Duration of analgesia-	Levobupivacaine group 292.8mins

Trial Locations

Locations (1)

St Stephens Hospital; 🇮🇳 Delhi, DELHI, India

St Stephens Hospital

🇮🇳Delhi, DELHI, India

Pramila Soni

Principal investigator

8447923480

drpramilasoni22@gmail.com