Pulmonary Hypertension in preterm children born at gestational age <30 weeks: Prevalence, risk factors and outcome.

Completed

• Conditions: Pulmonale hypertensie; Pulmonary Hypertension; High pressure in the lungs; 10019280; 10028971

• Registration Number: NL-OMON44035
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 165

Inclusion Criteria

All premature infants, admitted at the neonatology UMCG, born <30 weeks or birth weight < 1000 gram, who participate in NeolifeS

Exclusion Criteria

no informed consent.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The presence of PH (incidence and prevalence). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Morbidity, Mortality: Quality of life questionnaire and survival.<br /><br><br /><br>Maternal factors: mode of conception, delivery, preterm premature rupture of<br /><br>membranes, maternal disease history, illnesses during gestation, tabacco and<br /><br>medication use.<br /><br><br /><br>Perinatal variables: slow growth patterns in utero, prenatal echo findings,<br /><br>PROM, chorionamniotis, oligoamnion, birth events, placental histology.<br /><br><br /><br>Neonatal variables: development of BPD, low birth weight, gestational age,<br /><br>skull circumference, pulmonary and artficial ventilation variables, oxygen<br /><br>need, presence of PDA, medication, infections, renal function, complications<br /><br>(NEC), slow growth at GA 36wks and at discharge.<br /><br><br /><br>other: demographics, slow growth, admissions, medication, feeding, neurological<br /><br>development, respiratory symptoms, lung clearing index.</p><br>