Metformin as an adjuvant therapy for autism

Phase 2

Recruiting

• Conditions: Autism spectrum disorder.; Autistic disorder; F84.0

• Registration Number: IRCT20090117001556N156
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Age between 5-11 years
Diagnosis of autism spectrum disorder based on DSM-V
Patients who have specific behavioral problems such as aggression, hyperactivity, unusual, and stereotyped behaviors

Exclusion Criteria

An active medical disease
Diagnosis of another psychological disorder in DSM
History of previous sensitivity and intolerance to metformin
History of seizure and liver disorders
Taking antipsychotic drugs such as Risperidone before entering the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of irritability. Timepoint: Baseline and weeks 5, and 10. Method of measurement: By Aberrant Behavior Checklist-Community (ABC-C).