Influence of Enzyme Rich Malt Extract on gut health symptoms of irritable bowel syndrome in adults

Not Applicable

Completed

• Conditions: Irritable Bowel Syndrome; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621000513819
• Lead Sponsor: Edith Cowan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-05-03
• Study Completion: 2022-02-28
• Last Update Posted: 15 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

Male and female participants will be between 18 - 65 years old and have been clinically diagnosed with IBS, meeting the Rome IV edition diagnostic criteria

Exclusion Criteria

•Smoking,
•Pregnancy or planning to become pregnant,
•Breastfeeding,
•Having a known diagnosis of other gastrointestinal illness (e.g. Inflammatory Bowel Disease, malabsorption of any macronutrients, bowel resection, coeliac disease),
•Previous abdominal or gastrointestinal surgeries, severe mental health and sleep-related conditions (e.g. insomnia), renal or hepatic diseases, and major medical illness,
•Current use of pharmaceutical agents that could modify or treat IBS (e.g. probiotics, antibiotics, eluxadoline, lubiprostone and linaclotide),
•Other restrictive dietary patterns or therapies (e.g. gluten-free, low-carbohydrate, or high-protein diets, keto/Paleo-diet),
•Taken antibiotics or prebiotics in the past 6 weeks,
•Any other known disease, condition or habit that may interfere with completion of study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in IBS-related symptoms assessed with the Hunter IBS questionnaire and bowel symptom checklist[Baseline and following each of the 4 week placebo and malt extract diet interventions]