Can a nutritional omega-3 fatty acid formulation improve brain health in NCAA football athletes over the course of a season?
- Conditions
- utritional invervention study in a healthy, athletic, male populationNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN90306741
- Lead Sponsor
- Struct Nutrition, LLC
- Brief Summary
2018 Abstract results in http://dx.doi.org/10.1249/01.mss.0000538391.08920.b4 conference abstract (added 07/10/2019) 2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29807487 control group results (added 07/10/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34579748/ results (added 29/09/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 66
Players of NCAA Division I and III teams
1.Younger than 18 years of age
2. The use of long-term anti-inflammatory therapy (= 20 days)
3. The use of anti-hypertensive medications
4. The use of medications known to affect blood lipids
5. The consumption of fish oil or omega-3 FA supplementation
6. Self-reported consumption of more than two servings of fish per week
7. Athletes who were injured (including concussive injuries), became ill, were unable to participate in regularly scheduled conditioning, practice, or competitions, or those who did not meet the threshold compliance standards for daily supplementation (= 80%) were excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Serum Nf-L levels.<br> Blood was obtained from participants at various time points chosen to coincide with changes in practice intensity, the amount of physical contact, and the number and magnitude of head impacts<br>
- Secondary Outcome Measures
Name Time Method Plasma fatty acids levels sampled as above