ISRCTN80857707已完成不适用
The effect of omega-3 polyunsaturated fatty acid dose level on hyperpnoea-induced bronchoconstriction and markers of airway inflammation in asthma
ottingham Trent University (UK)0 个研究点目标入组 108 人开始时间: 2016年5月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 108
研究概览
简要总结
2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28606216
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Male
入选标准
- •1. Body mass index (BMI) 20-25 kg.m-2
- •2. Physically active 3 or more times a week , with each exercise session lasting at least 45 min
- •3. Non-smoker
- •4. Non-vegetarian or vegan
- •5. Asthma sufferers must have own clinically prescribed medication
- •6. Asthma sufferers must have a GP diagnosis
排除标准
- •1. Predicted forced expiratory volume in 1 second (FEV1) less than 65%
- •2. Previously diagnosed with COPD, emphysema, chronic bronchitis or similar respiratory illness
- •3. Previously admitted to hospital for asthma or other breathing difficulties
- •4. Asthma exacerbation within the last month (course of steroids or hospital visit)
- •5. History of heart failure, pulmonary hypertension, embolism, or other pulmonary heart disease
- •6. History of recurrent chest infections
- •8. Acute infection within the last four weeks
- •9. Major operation within the past four months
- •10. Have a history of taking ?-3 PUFA supplements or supplements with antioxidants above recommended intake, or consume more than three fatty fish meals per week
- •11. Take a daily dose of aspirin or other NSAIDs
- •12. Currently taking a daily dose of anti-histamine
- •13. Currently taking long-term asthma maintenance medications – corticosteroids, and leukotriene modifiers that you could not refrain from taking for 4 days prior to laboratory session
研究者
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