IRCT201611241031N19
Completed
Phase 1
Autologous bone marrow derived mononuclear cells (BMMNCs) subfacial transplantation in idiopathic lymphedema patients: clinical trial phase I
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Royan Institute
- Enrollment
- 6
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age between 10\-35 years; Idiopathic lower limb lymphedema; Grade less than III ; Resistant to conventional therapy; Informed consent.
- •Exclusion criteria:
- •Heart Failure (EF less than 45%); Renal failure (Cr more than 2\) ; Hepatic failure (LFT more than 3 times) ; History of related surgery (lymph node dissection); History of Autoimmune disease; History of trauma or infection; History of pelvic malignancy or treatment for malignancy (Irradiation); Symptoms of sleep apnea; Previous bone marrow transplant; Morbid obesity or Lipedema (BMI \= 40\); Allergic disorders; Cytotoxic drugs; Drugs induced lymphedema; Congenital vascular malformation; Myxedema; Traveling to tropical countries or suspicion to filariasis; Dependency.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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