Efficacy of Erector Spinae Plane Block on Postoperative Analgesia and Recovery After Off Pump Cardiac Surgery: A Randomised Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Total intraoperative and postoperative opioid consumption
研究概览
简要总结
In this study the investigators will investigate the efficacy of ESPB as a part of Enhanced recovery after surgery on postoperative analgesia and recovery criteria after off pump cardiac surgery.
详细描述
General anaesthesia will be induced by 0.05 mg/kg midazolam, 3 µg/kg fentanyl, 1-2mg/kg propofol, and 0.5mg/kg of Atracurium. After induction, bilateral erector spinae plane block will be performed in the block group. Intraoperative analgesia will be achieved by fentanyl boluses of 0.5-to-1 µg/kg titrated according to haemodynamic parameters. Postoperative analgesia will be managed by paracetamol 1000 mg /6hours and morphine 1-2mg boluses when pain score ≥4 1 to 2 mg to be repeated every 5 minutes if needed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-70 years
- •ejection fraction of > 45%
- •undergoing elective off-pump cardiopulmonary bypass surgery
排除标准
- •vertebral anomalies
- •intra-aortic balloon pump in the preoperative period
- •acute myocardial infarction
- •local infection at the site of block
- •allergy to the local anesthetic used
- •morbid obesity, psychiatric disorders, neurologic deficits, alcohol and chronic opioid abuse, and patients with bleeding diathesis.
研究组 & 干预措施
Erector spinae block group
the patients will be administered bilateral Erector spinae block with 20 ml of 0.25 % bupivacaine
干预措施: Erector spinae block (Procedure)
Erector spinae block group
the patients will be administered bilateral Erector spinae block with 20 ml of 0.25 % bupivacaine
干预措施: Fentanyl (Drug)
control group
no block will be done but only IV analgesia.
干预措施: Fentanyl (Drug)
结局指标
主要结局
Total intraoperative and postoperative opioid consumption
时间窗: 48 hours
Microgram and mg
次要结局
- The heart rate(48 hours)
- mean arterial blood pressure(48 hours)
- pain intensity at rest and movement(48 hours)
- time to extubation(24hours)
- time to ambulation(24hours)
- time to oral intake(48 hours)
- time to first rescue analgesia(24hous)
- time of chest drain removal(5 days)
- time of intensive care unit stay(one week)
- Duration of mechanical ventilation(24 hours)
研究者
Amal Gouda Elsayed Safan
lecturer of anaethesia
Menoufia University