rhTPO Mobilized Auto Cryo Platelets For GYN Patients Receiving Carboplatin
Not Applicable
Completed
- Conditions
- Neoplasms, Gynecologic
- Interventions
- Registration Number
- NCT00038012
- Lead Sponsor
- M.D. Anderson Cancer Center
- Brief Summary
A Pilot Study of Transfusion of rhTPO-Derived Autologous Platelets Cryopreserved with ThromboSol and 2% DMSO in Patients with Gynecologic Malignancy Receiving Carboplatin
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 33
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description rhTPO-Derived Autologous Platelets Transfusion Platelet-pheresis - rhTPO-Derived Autologous Platelets Transfusion Thrombopoietin - rhTPO-Derived Autologous Platelets Transfusion Carboplatin -
- Primary Outcome Measures
Name Time Method Response Rate Continuous
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie rhTPO-stimulated platelet production in gynecologic cancer patients?
How does rhTPO-derived cryopreserved platelet transfusion compare to standard platelet products in carboplatin-induced myelosuppression management?
Which biomarkers correlate with successful platelet recovery after rhTPO mobilization in gynecologic malignancy patients?
What are the safety profiles and adverse event management strategies for rhTPO platelet cryopreservation using Thrombosol and DMSO?
What combination therapies with thrombopoietin agonists are being explored for gynecologic cancer patients undergoing platinum-based chemotherapy?
Trial Locations
- Locations (1)
MD Anderson Cancer Center
🇺🇸Houston, Texas, United States
MD Anderson Cancer Center🇺🇸Houston, Texas, United States