Assessing the Health Impact of a Combined Water and Sanitation Intervention in Rural Odisha, India

• Conditions: Diarrhea; Enteric Infection; Soil-transmitted Helminth Infection; Stunting

• Registration Number: NCT02441699
• Lead Sponsor: London School of Hygiene and Tropical Medicine

Brief Summary

This is a matched-cohort study designed to assess the health impact of a rural demand-driven water and sanitation intervention that provides piped treated water and household level pour-flush latrines and bathing rooms, as implemented by Gram Vikas.

Detailed Description

We will undertake a matched-cohort study among 84 villages in Ganjam district, Orissa, India to assess the health impact of a program that provides improved water supplies and sanitation to rural villages.

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2015-04-27
• Study First Submitted QC: 2015-05-07
• Study First Posted: 2015-05-12
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-20
• Last Update Posted: 2019-08-21
• Primary Completion: 2019-12
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2940

Inclusion Criteria

• Households in participating villages will be eligible to participate in the study if they have at least one child under 5 years.

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reported diarrhoea in children <5 years	7-day recall, assessed 4 times during 3-month follow-up rounds

Secondary Outcome Measures

Name	Time	Method
Soil-transmitted helminth infection	Point prevalence assessed in rounds 2 (approximately 90-120 days after study commencement) and 4 (approximately 240 to 360 days after study commencement)	Stool samples taken and assayed for ascaris, trichuris, hookworm
Reported lower respiratory infection in children <5	7-day recall, assessed 4 times during 3-month follow-up rounds
Diarrhoea among all ages	7-day recall, assessed 4 times during 3-month follow-up roundsits
Lower respiratory infection among all ages	7-day recall, assessed 4 times during 3-month follow-up roundsts
Biomarkers of environmental enteropathy and enteric infection	Assessed once during round 3 (approximately 180 to 240 days following commencement of study
Height-for-age among children < 2 years	Assessed approximately every 90 days for a total of four measurement over study period	Children height measured and HAZ scores computed
Weight-for-age among children <5	Assessed approximately every 90 days for a total of four measurement over study periodAssessed during all four follow up rounds	Children weighed and WAZ scores computed

Trial Locations

Locations (1)

London School of Hygiene & Tropical Medicine; 🇬🇧 London, United Kingdom