An Investigation of Different Type Single Limb Exercise Training Effects in Copd
- Conditions
- Exercise
- Interventions
- Other: single leg exercise intervantion in COPD
- Registration Number
- NCT06471439
- Lead Sponsor
- Hacettepe University
- Brief Summary
COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise limitation is observed in COPD. Especially, decreased exercise performance related to vascular and fatique in quadriceps muscle. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and fatigue are observed in COPD. One leg exercise training result is not enough to highlight these parameters.
Three types single leg exercise intervantion will be applied. Exercise capacity, muscle strength, lung function, electromyography, lactate and quality of life will be measured.
- Detailed Description
Three types single leg exercise intervantion will applied to COPD patients that devided three groups. One leg continuous exercise training will be aplied to one group. One leg HIIT exercise training will be aplied to other group. One leg resistance exercise training will be aplied to the last group.
Exercise capacity and muscle strength are assesed. Lung function is measured. Electormyography is recorded. Lactate and quality of life are measured.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 66
- COPD patients that applied to physiotherapy
- Cooperation for tests
- without severe ortopedical and neurological disease
- without severe cardiovascular disease
- To volunteer for the study.
- have an acute exacerbation or having exacerbation at last month
- hypoxemia (PaO2<55mmHg)
- no cooperated to test without volunteer to study having ortophedical and neurological diesase that affecting of tests severe cardiovascular disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description single leg resistance exercise intervantion in COPD single leg exercise intervantion in COPD single leg resistance exercise intervantion in COPD will be perfomed at six weeks single leg high intensity exercise intervantion in COPD single leg exercise intervantion in COPD single leg high intensity exercise intervantion in COPD will be perfomed at six weeks single leg continous exercise intervantion in COPD single leg exercise intervantion in COPD single leg continous exercise intervantion in COPD will be perfomed at six weeks
- Primary Outcome Measures
Name Time Method six minute walk test pre-intervention six minute walk test in meter
- Secondary Outcome Measures
Name Time Method cardiopulmonary exercise test beginning day 2 VO2 as ml/kg/min will be recorded from incremental cycle cpet test
isometrics quadriceps muscle strength assesing beginning day 1 and last day quadriceps muscle isometric muscle strength will be recorded at kilogram
one leg cardiopulmonary exercise test beginning, day 3 VO2 as ml/kg/min will be recorded from incremental cycle cpet test
quadriceps muscle strength assesing (repeated measeure) beginning day 1 and last day quadriceps muscle 10 repeated max muscle strength will be recorded at kilogram,
arterial stiffness beginning day 2 and last day total vascular resitance, augmentation index @ 75 and pulse wave velocity wil be determined arterial stiffness
lung function beginning day 1 and last day FEV1/FVC ratio in %
quality of life assesing beginning day 1 and last day total score in 0-100 range
lactate measurement beginning day 2 and last day lactate in mmol
electromyography measurement beginning day 2 and last day precentage of maximum volunteer contraction) %MVC values will be presented muscle fatigue (median frequence) and activation will be shown electromyograpy (EMG)
Trial Locations
- Locations (1)
Elif Kocaaga
🇹🇷Ankara, Turkey