An Investigation of Different Type Single Limb Exercise Training Effects on Functional Capacity, Arterial Stifness, Muscle Activation and Quality of Life in Chronic Obstructive Pulmonary Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Exercise
- Sponsor
- Hacettepe University
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- six minute walk test
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise limitation is observed in COPD. Especially, decreased exercise performance related to vascular and fatique in quadriceps muscle. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and fatigue are observed in COPD. One leg exercise training result is not enough to highlight these parameters.
Three types single leg exercise intervantion will be applied. Exercise capacity, muscle strength, lung function, electromyography, lactate and quality of life will be measured.
Detailed Description
Three types single leg exercise intervantion will applied to COPD patients that devided three groups. One leg continuous exercise training will be aplied to one group. One leg HIIT exercise training will be aplied to other group. One leg resistance exercise training will be aplied to the last group. Exercise capacity and muscle strength are assesed. Lung function is measured. Electormyography is recorded. Lactate and quality of life are measured.
Investigators
Elif Kocaaga
principal investigator
Hacettepe University
Eligibility Criteria
Inclusion Criteria
- •COPD patients that applied to physiotherapy
- •Cooperation for tests
- •without severe ortopedical and neurological disease
- •without severe cardiovascular disease
- •To volunteer for the study.
Exclusion Criteria
- •have an acute exacerbation or having exacerbation at last month
- •hypoxemia (PaO2\<55mmHg)
- •no cooperated to test without volunteer to study having ortophedical and neurological diesase that affecting of tests severe cardiovascular disease
Outcomes
Primary Outcomes
six minute walk test
Time Frame: pre-intervention
six minute walk test in meter
Secondary Outcomes
- cardiopulmonary exercise test(beginning day 2)
- isometrics quadriceps muscle strength assesing(beginning day 1 and last day)
- one leg cardiopulmonary exercise test(beginning, day 3)
- quadriceps muscle strength assesing (repeated measeure)(beginning day 1 and last day)
- arterial stiffness(beginning day 2 and last day)
- lung function(beginning day 1 and last day)
- quality of life assesing(beginning day 1 and last day)
- lactate measurement(beginning day 2 and last day)
- electromyography measurement(beginning day 2 and last day)