Acute Effects of Three Different Types Single Leg Exercise in Copd

Not Applicable

Recruiting

• Conditions: Exercise
• Interventions: Other: single exercise bout about one-leg exercise

• Registration Number: NCT06466213
• Lead Sponsor: Hacettepe University

Brief Summary

COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and muscle oxygenation are observed in COPD. One leg exercise result is not enough to highlight these parameters.

Detailed Description

Acute Effects of Three Different Types Single Leg Exercise in Copd

single bout high intensity interval training

single bout continuous exercise training single bout resistance training

Study Timeline

• Study Start: 2024-02-20
• Study First Submitted: 2024-05-17
• Status Verified: 2024-06
• Study First Submitted QC: 2024-06-17
• Last Update Submitted: 2024-06-17
• Study First Posted: 2024-06-20
• Last Update Posted: 2024-06-20
• Primary Completion: 2025-01-02
• Study Completion: 2025-01-02

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• COPD patients that applied to physiotherapy
• cooperate to test
• no severe ortopedical and neurological disease no severe cardiovascular disease volunteer to study

Exclusion Criteria

• have an acute exacerbation
• hypoxemia [PaO2] <55 mmHg
• no cooperated to test no volunteer to study having ortophedical and neurological diesase that affecting of tests having severe cardiovascular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
single session one leg exercise intervantion in COPD	single exercise bout about one-leg exercise	first session: single session leg Continuous exercise intervantion will be applied to COPD. Unilaterally single leg continuous exercise will be performed as only one session second session : single session leg high intensity interval exercise intervantion will be applied to COPD. Unilaterally single leg hııt exercise will be performed as only one session third sessionsingle session leg resistance exercise intervantion will be applied to COPD. Respirocally leg strength (knee extantion ) exercise will be performed

Primary Outcome Measures

Name	Time	Method
six minute walk test	beginning, day 1	six minute walk test in meter

Secondary Outcome Measures

Name	Time	Method
strength training acute exercise (single leg)	beginning day 4,5,6	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
arterial stifness	beginning day 2,3, 4,5,6	Aıx@75 in %
continous exercise acute (single leg)	beginning day 4	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
high intensity interval training acute exercise (single leg)	beginning day 5	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
cardiopulmonary exercise test	beginning, day 2	VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test
lung function	beginning, day 1	FVC in % , FEV1 in %, FEV1/FVC ratio, PEF in % and FEF 25-75 in %
muscle strength (10 repeated max)	beginning, day 1	quadriceps 10 repeated max muscle strength will be recorded as kilogram
muscle oxygenation	beginning day 4,5,6	minumum muscle oxygenation level will be presented as percentage
single leg extremity test	beginning, day 3	VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test
muscle strength (isometric)	beginning day 1	quadriceps isometric muscle strength will be recorded as kilogram

Trial Locations

Locations (1)

Elif Kocaaga; 🇹🇷 Ankara, Turkey