Post-operative Cognitive Dysfunction and the Change of Regional Cerebral Oxygen Saturation in Elderly Patients Undergoing Spinal Surgery
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Elderly Patients Undergoing Spinal Surgery
- Sponsor
- Yonsei University
- Enrollment
- 87
- Locations
- 1
- Primary Endpoint
- K-MMSE
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
Post operative cognitive dysfunction (POCD) is a well-recognized complication of patients undergoing cardiac surgery. Previous studies reported near-infrared spectroscopy provides information on the occurrence of cerebral desaturation resulted in POCD. But evidence of POCD after general surgery has been lacking. Especially, the prone position is used primarily for surgical access to the posterior spine, if there is any significant lowering of the legs or tilt of the entire table, venous returns may be decrease or augmented accordingly. The purpose of this study was to examine the relationship between POCD and intra-operative cerebral oxygen saturation after spine surgery in elderly patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •the patient undergoing the lumbar spine surgery in severance hospital
Exclusion Criteria
- •Patients who had previous cerebral disease, dementia, severe problems in hearing and understanding, or who were unable to provide informed consent were excluded.
Outcomes
Primary Outcomes
K-MMSE
Time Frame: change of K-MMSE from baseine to 1 month
1. preoperative neuropsychological evaluation (the day before the surgery) 2. intraoperative rSO2 data monitoring 3-1. immediate postoperative neuropsychological evaluation (postoperative 4th\~7th day) 3-2. remote postoperative neuropsychological evaluation (postoperative 1month) 4. Intraoperative
Secondary Outcomes
- visuomotor test(D-LOTCA battery)(measuring for visuomotor test during baseline and 1 month)
- Regional cerebral oxymetry monitoring(measuring for Regional cerebral oxymetry monitoring during baseline and 1 month)