跳至主要内容
临床试验/CTRI/2024/09/074459
CTRI/2024/09/074459尚未招募3 期

A Randomised Open Label Controlled Clinical Study to Evaluate the Efficacy of Pathya Ahara along with Rasonadi Kwatha and Rasonadi Kwatha alone in the management of Amavata with special reference to Rheumatoid Arthritis

Jammu Institute of Ayurveda and Research Jammu1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年10月15日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Subjective Parameters:

研究概览

简要总结

Health is supreme foundation for the achievement of happy life. The sedentary life style of

today’s era has increased the risk of certain disorders like diabetes, hypertension and joint

pathologies. The disorders affecting the locomotory system are increasingly seen in the

present time. Among such disorders Ayurveda classics have described a debilitating

disease called AMAVATA.

It is not only a disorder of the locomotor system, but is also a systemic disease and is named

after its chief pathogenic constituents, which are, Ama and Vata. The disease typically

manifests itself with localized symptoms like Sandhishoola, Shotha and Stabdhata in the

joints of Hasta, Pada-Shira, Gulpha, Janu, Trika and Uru along with symptoms of systemic

manifestation like Angamarda. Aruchi, Trushna, Aalasya, Gourava, Jwara, Apaka and

Angashoonata1

. The disease ‘Amavata’ resembles the aetiopathogenesis and clinical

picture observed in Rheumatoid Arthritis of conventional medicine2

. Rheumatoid Arthritis

which is a systemic chronic inflammatory joint disorder which affects predominantly the

synovial joints. Cardiac involvement, symmetrical involvement of joints along with Pain,

Stiffness and Swelling with number of systemic complication resembles the disease

Amavata . Pathya,which is the Aahar- vihar that calms the mind, is beneficial to the body,

and provides nutrients, and Apathya, which is the opposite of Pathya 3

(Ch . Su 25 / 45 ).

Importance of Pathya :

Acharya Charaka had detailed Pathya as a synonym for treatment4

. He mentioned that

when channels of circulation become hard by aggravated Doshas and Pathya helps to

soften the Srotasas and alleviate vitiated dosha5.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
16.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients having Cardinal Signs and Symptoms of Amavata will be considered for present study
  • Patients of both the gender between the age group of 16-60 years presenting Clinical
  • Patients who follow the American College of Rheumatology (ACR) 2010 Criteria.

排除标准

  • Patients aged below 16 years and above 60 years.
  • Gout, Osteoarthritis, Ankylosing Spondylitis, Osteomyelitis
  • Pregnant and lactating women.
  • Arthritis with malignancy.
  • Ulnar deviation, Swan neck deformity of wrist and elbow.
  • Patient suffering from other systemic complicated diseases like Diabetes Mellitus, Pulmonary Tuberculosis, Hyperthyroidism, Hypothyroidism etc.

结局指标

主要结局

Subjective Parameters:

时间窗: Baseline

The Signs and Symptoms of Amavata as per Ayurvedic classics:

时间窗: Baseline

 Sandhistabdhata (Morning stiffness)

时间窗: Baseline

 Sandhishoola (Pain)

时间窗: Baseline

 Sandhishotha (Swelling)

时间窗: Baseline

 Apaka (Indigestion)

时间窗: Baseline

Objective Parameters:

时间窗: Baseline

ï‚§ ESR

时间窗: Baseline

ï‚§ R.A Factor

时间窗: Baseline

ï‚§ CRP

时间窗: Baseline

次要结局

  • 1.Range of movement of affected joints.(2.Number of joints involved)

研究者

发起方
Jammu Institute of Ayurveda and Research Jammu
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Kajal Raskotra

Jammu Institute of Ayurveda and Research Jammu

研究点 (1)

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