Resting Energy Expenditure in the First 72 hours of Pediatric Sepsis: Indirect calorimetry vs Schofield equatio

Completed

• Conditions: Pediatric sepsis; sepsis, energy expenditure, measure REE, pediatric sepsis, indirect calorimetry

• Registration Number: TCTR20240706006
• Lead Sponsor: Ratchadapiseksompotch Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-03-31
• Study Start: 2024-07-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

We enrolled patients under 15 years old diagnosed with sepsis by the 2005 International Pediatric Sepsis Consensus Conference criteria who admitted to our 10-bed pediatric intensive care unit (PICU), serving medical and surgical conditions, at King Chulalongkorn Memorial Hospital from March 2023 to March 2024.

Exclusion Criteria

Critical airway patient, Risk of airborne infection, Pneumothorax or air leak or mechanical ventilator leakage >10%, On extracorporeal therapy, On nasal oxygen support or non-invasive mechanical ventilator, On high mechanical ventilator setting
(FiO2 > 60%, PEEP > 10 cmH2O, on HFOV), Underweight (body weight < 10 kg)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
energy expenditure 2,6,12,24,72 hours after diagnosis indirect calorimetry

Secondary Outcome Measures

Name	Time	Method
measure REE to predicted REE 2,6,12,24,72 hours after diagnosis energy expenditure form indirect calorimetry and equation,explore the relationship between the parameter derived from IC and disease severity using predicted death rate 2,6,12,24,72 hours after diagnosis PELOD-2 score and PIM-3 score.