Hypoalgesic Effects of Specific vs Non-specific Cervical Manipulation in Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Pressure Pain Threshold at the posterior region of the forearm
研究概览
简要总结
This study evaluates the hypoalgesic effect of global and specific cervical joint manipulation in healthy individuals. At first the participants received one of the interventions and after 48 hours, the other.
详细描述
Cervical Joint Manipulation (CJM) are often used for pain treatment.
Joint manipulation generates a series of stimuli within the central nervous system through the activation of proprioceptors located in the joint capsule or muscles, stimulates the PAG, causing pain inhibition by activation of non-opioid descending inhibitory pathways.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Examiner 1 will receive the blinding outcome will be asked: "Which intervention does the patienth as received: global manipulation or especific manipulation" Their responses to these questions will be recorded and used to measure the adequacy of participants and examiners.
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects of both sexes
- •without pain complaints in the last 90 days
排除标准
- •previous spinal surgeries
- •spinal canal stenosis
- •vertebral fracture
- •spondylolisthesis
- •acute infections
- •hemorrhagic disorders
- •active tuberculosis
- •deep vein thrombosis
- •osteoporosis
- •rheumatic diseases
- •metabolic diseases
- •cardiorespiratory diseases
- •smoking injury
- •musculoskeletal injury
- •use of pacemaker
- •women in menstrual period
- •pregnant women
- •use of pain-killers in the last 48 hours
- •use of anti-inflammatory drugs in the last 48 hours
- •previous joint manipulation treatments
- •aversion to cervical joint manipulation
- •positivity in the vertebral artery test
- •headache in the last seven days
研究组 & 干预措施
Global manipulation
Manual therapy performed in the cervical region in a non-specific way.
干预措施: Global manipulation (Device)
Especific manipulation
manual therapy performed specifically on the C6-7 segment
干预措施: Especific manipulation (Device)
结局指标
主要结局
Pressure Pain Threshold at the posterior region of the forearm
时间窗: 1 minute after the end of the intervention.
The subjects were placed supine on a stretcher with their elbows fully extended and the anterior portion of the forearm resting on the stretcher. Subjects were instructed to keep their eyes closed during attempts. The examiner used a Somedic Type II digital pressure algometer (Somedic Inc, Hörby, Sweden) on the posterior region of the forearm 10cm below the lateral epicondyle of the elbow towards the third finger, keeping the forearm in pronation. The pressure was then applied perpendicular to the skin at a rate of 40kPa / s using a 1cm2 flat circular probe covered with 1mm of rubber to prevent any skin pain caused by sharp metal edges.
次要结局
未报告次要终点
研究者
Jonathan Daniel Telles
Principal Investigator
Universidade Federal de Sao Carlos