Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Change from baseline using the Numeric Rating Scale for Pain at 1 hour
研究概览
简要总结
The purpose of these study is to compare the effectivity of the Cervical Lateral Glide physical therapy neural mobilization technique to the complete absence of treatment in a group of patients who suffer cervicobrachial pain.
详细描述
The Cervical Lateral Glide (CLG) is a neural tissue mobilization technique capable of achieving a hypoalgesic effect during the onset of cervicobrachial pain symptoms. This happens through a series of complex physiologic interactions which are not fully understood. The CLG Physical therapy technique consists of controlled movements of the cervical and brachial plexus neural tissue. Hypoalgesic effect produced by CLG is associated to an increase in neural tissue mobility, edema, inflammation and intraneural pressure reduction, without any known side effects when applied properly, except for a momentary worsening of symptoms (the only known side effect of CLG), which is an important contrast to the wide and sometimes severe spectrum of side effects derived from drug therapy used to treat cervicobrachial pain.
It is believed that the hypoalgesic effect offered by neural tissue mobilization is a consequence of descending nervous system pain modulation activity and an improvement in the distinct biomechanical properties of the involved neural tissue.Despite the increase in scientific interest in evidence based options to treat pain and neural tissue mobilization techniques there is a current lack of enough controlled double blind clinical trials that measure the effectiveness of neural tissue mobilization techniques such as the CLG and its specific effect over cervicobrachial pain. For this reason the present investigation consisted in the application of a treatment protocol based on CLG neural tissue mobilization in a controlled double blind clinical trial with the aim to assess its clinical effectiveness in treating pain symptoms
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of cervicobrachial pain confirmed by magnetic resonance imaging
- •Presence of unilateral symptoms of arm pain, paresthesia or numbness in the upper extremity during at least 3 continuous months previous to the application of treatment.
- •Positive results in all of the following tests: Spurling, Distraction, and Upper Limb
排除标准
- •Contraindication in the use of nonsteroidal anti inflammatory drugs (NSAIDs)
- •The use of any type of treatment, therapy, procedure or drug to relieve pain
- •Patients who are under anticonvulsant, antidepressant or psychotropic medication
- •Vertebral instability
- •Vertebral osteoporosis
- •Vertebral or spine infection.
- •Neurologic diseases of genetic, infectious or neoplastic origin
- •Cervical stenosis myelopathy
- •Pregnancy
- •Kinesiophobia
- •Endocrine disorders and menopause
- •History of spine surgery
- •Intellectual disability, severe mental illness, intoxication, severe sleep deprivation, Alzheimer's disease.
研究组 & 干预措施
Cervical Lateral Glide
- 15 minutes Cervical Lateral Glide neural mobilization
- 5 times a week
- During 6 weeks
- Patient's adequate cervical spine linear alignment was determined through the baseline use of a Universal Goniometer Device in each application of Cervical Lateral Glide neural mobilization.
干预措施: Cervical Lateral Glide neural mobilization (Procedure)
Waiting list control group
- Patients assigned to a 6 week waiting list to receive treatment
结局指标
主要结局
Change from baseline using the Numeric Rating Scale for Pain at 1 hour
时间窗: at baseline for both arms and 1 hour after the application of treatment only in the experimental arm, corresponding to intervention days 1, 15 and 30
the Numeric Rating scale for Pain (NRS) is an 11 point scale for patient self reporting of pain in which 0 points represents the total absence of pain and 10 points the worst state of pain, it was employed to evaluate the presence and relieve of cervicobrachial pain symptoms.
次要结局
- Change from baseline of the Physical function involving the affected upper limb using the Quik DASH Scale(at baseline, corresponding to intervention days 1 and 30 of treatment)
- Cervical Rotation Range of Motion (CROM)(at baseline for both arms and 1 hour after the application of treatment only in the experimental arm, corresponding to intervention days 1 and 30)
研究者
Francisco Unda Solano
PHD Student
Universidad Europea de Madrid