The Application of Neuromodulation in Sciatic Nerve

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Neuromodulation

• Registration Number: NCT05549700
• Lead Sponsor: University of Seville

Brief Summary

The objective of this study will be to analyze the muscle activity of the short head (SHBF) and long head of the biceps femoris (LHBF) after the application of ultrasound-guided percutaneous neuromodulation (NMP) in the tibial or common fibular nerve compartment of the sciatic nerve.

Authors will recruit healthy subjects and they will receive asymmetric biphasic rectangular current through a needle into the sciatic nerve. The sample was divided into two groups: one to which the technique was applied in the lateral compartment and another group, in the medial compartment of the nerve. The protocol used was 5 seconds of stimulation, 55 seconds of rest for 5 minutes at a frequency of 100 Hz and a phase duration of 350 microseconds. The electrical activity (recruitment of muscle fibers and maximum contraction) of the SHBF and LHBF and the muscle strength of the knee flexors were recorded by requesting the participants isometric flexion of the knee in the prone position. The percentage of change of each variable was also analyzed.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-09-15
• Study First Submitted QC: 2022-09-19
• Study First Posted: 2022-09-22
• Status Verified: 2022-12
• Study Start: 2022-12-01
• Primary Completion: 2022-12-02
• Study Completion: 2022-12-30
• Last Update Submitted: 2022-12-31
• Last Update Posted: 2023-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

• Healthy volunteer

Exclusion Criteria

• Subjects that have lumbar area of the back, scoliosis, lower limb dysmetria
• Subjects undergone any surgical intervention in the lumbar area or lower limbs
• Subjects that present acute or unresolved injury in the last 6 months in the lower limbs
• Subjects under treatment drug treatment
• Subjects that they are afraid of needles or electric current
• Subjects with epileptic
• Pregnant.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Common fibular nerve group	Neuromodulation	The subjects of this group will receive electric nerve stimulation on the sciatic nerve through a lateral approach to stimulate the behavior corresponding to the common fibular nerve
Tibial nerve group	Neuromodulation	The subjects of this group will receive electric nerve stimulation on the sciatic nerve through a lateral approach to stimulate the behavior corresponding to the tibial nerve

Primary Outcome Measures

Name	Time	Method
Electrical muscular activity	3 months	recruitment of muscle fibers, measured by electromyography (microvolts)
muscle strength of the knee flexors	3 months	strength measured by dynamometer (Kg)

Trial Locations

Locations (1)

Blanca; 🇪🇸 Seville, Sevile, Spain