IRCT20200907048644N1
Recruiting
Phase 1
Evaluation of short-term effects of Celecoxib on clinical improvement of COVID-19 patients: A randomized clinical trial study
Zahedan University of Medical Sciences0 sites60 target enrollmentStarted: TBDLast updated:
Overview
- Phase
- Phase 1
- Status
- Recruiting
- Sponsor
- Zahedan University of Medical Sciences
- Enrollment
- 60
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 65 years (—)
- Sex
- All
Inclusion Criteria
- •Subjects with COVID\-19 in the second phase of the disease
- •Shortness of breath, chest pain with or without fever equal to or greater than 38 'C
- •Blood oxygen saturation (SpO2\) between 90\-93%
- •Adult patients with COVID\-19 with moderate pulmonary involvement and hospitalized in the general ward who have been diagnosed and confirmed with coronavirus by conventional diagnostic methods such as sequencing or qRT\-PCR and CT (within 48 hours of admission)
- •Age range of patients between 18\-65 years
- •Existence of pneumonia in lung CT scan with involvement of maximum 3 or 4 lung lobes or less than one third of the volume of each lobe or infection of one or two lobes with larger area
- •Patients informed consent
Exclusion Criteria
- •Patients under 18 or over 65 years old
- •Patients with severe and advanced disease are admitted to the intensive care unit
- •Participate in another clinical trial
- •Shock and critical illness (requires ventilator and organ failure)
- •Patients with organ dysfunction such as renal failure and liver damage, patients with asthma
- •Taking certain medications such as furosemide or Lasex, lithium, ACE2 inhibitors
- •People with medical history such as high blood pressure, autoimmune diseases and ..
Investigators
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