Intermittent theta-burst stimulation (iTBS) as concomitant treatment for borderline personality disorder - a pilot study - DBTTMS

VR-Klinikum Düsseldorf, Kliniken der Heinrich-Heine-Universität0 个研究点目标入组 60 人开始时间: 2020年1月13日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Borderline Personality Disorder (DSM V) assessed through a standardized clinical interview (SKID V PD)
•- sufficient knowledge of German
•- Age: 18-45
•- No prior treatment with DBT
•- If medicated stable treatment with the medication for 2 weeks before commendement of the brain stimulation treatment. Medication should remain stable during the 4-weeks of brain stimulation.
•- Receiving inpatient or day-clinic, standardized, DBT-based treatment
•- Participants must be able to give consent to participate
•- Negative pregnancy test and being prepared to use contraception for the duration of brain stimulation treatment

•- history of seizures or epilepsy
•- metallic implants of the skull
•- extensive tatoos on the head
•- significant brain tumors or brain malformations
•- cerebrovascular events
•- traumatic brain injury
•- neurodegenerative disorders
•- brain surgery
•- deep brain stimulation
•- Pacemaker
•- severe somatic disorders
•- other psychiatric comorbidities (measured by Mini-DIPS-OA) except Depression
•- acute suicidality (MADRS Score >4 for Item 10)
•- tinnitus
•- pregnancy
•- claustrophoby
•- treatment with antiepileptic drugs
•- taking benzodiazepines in doses exceeding 1mg Lorazepam per day
•- patients under legal guardianship who require their guardian's approval to provide consent
•- treatment with electroconvulsive therapy in the current episode
•- current or prior treatment with deep brain stimulation, vagus nerv stimulation or other intracranial implants

发起方

VR-Klinikum Düsseldorf, Kliniken der Heinrich-Heine-Universität