临床试验/NCT00723268

NCT00723268Unknown2 期

Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae

Mashhad University of Medical Sciences1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2007年5月最近更新: 2008年7月29日

适应症

干预措施

试验速览

阶段: 2 期
发起方: Mashhad University of Medical Sciences
入组人数: 30
试验地点: 1
主要终点: frequency of ulcers

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine whether low doses of prednisolone, or colchicine are effective in the treatment of oral aphthae.

详细描述

Treatment of recurrent aphthous stomatitis (RAS) remains, to date, empirical and non-specific. The main goals of therapy are to minimize pain and functional disabilities as well as decrease inflammatory reactions and frequency of recurrences.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Single (Investigator)

入排标准

年龄范围: 15 Years 至 60 Years（Child, Adult）
性别: All
接受健康志愿者: 是

入选标准

•Confirmation of clinical diagnosis of aphthae
•Having the experience of oral aphthae at least once in a month
•Two weeks wash out periods after the last treatment

排除标准

•History of any systemic disease
•Using drugs which affect immune system
•Pregnancy and breast feeding
•Aphthous related syndromes

研究组 & 干预措施

Prednisolone

Active Comparator

干预措施: Prednisolone (Drug)

Colchicine

Active Comparator

干预措施: Colchicine (Drug)

结局指标

主要结局

frequency of ulcers

时间窗: 1 year

次要结局

未报告次要终点

研究者

发起方

Mashhad University of Medical Sciences

申办方类型

Other

研究点 (1)

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