The Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium

Completed

• Conditions: Cognitive Dysfunction, Cognitive Disorder; Delirium - Postoperative
• Interventions: Procedure: Sevoflurane

• Registration Number: NCT06597812
• Lead Sponsor: Amasya University

Brief Summary

In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.

Detailed Description

The patients were preoperatively assessed for American Society of Anesthesiologists (ASA) risk by an anesthetist and age, sex and comorbidities were recorded. The Mini-cog test was applied as a cognitive screening test by the anesthesiologist in the preoperative period and the test score was recorded. Three-word memory test, clock drawing, and visual function test was performed to evaluate the patient's cognitive functions. In this test, patients were asked to memorize three words such as umbrella, sunshine, and chair at the beginning of the test.

Study Timeline

• Study Start: 2023-03-01
• Primary Completion: 2023-10-01
• Study Completion: 2023-11-01
• Status Verified: 2024-09
• Study First Submitted: 2024-09-12
• Study First Submitted QC: 2024-09-14
• Last Update Submitted: 2024-09-14
• Study First Posted: 2024-09-19
• Last Update Posted: 2024-09-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

• There was a correlation between the incidence of delirium after the age of 60(10).

Exclusion Criteria

• Patients' age< 60 years,
• Patients undergoing emergency cholecystectomy or did not have preoperative Mini-Cog assessment,
• With a history of cerebrovaskuler insult that was thought to have an effect on postoperative delirium ,
• Patients with difficulty in cooperation ,
• Patients with hemodynamic instability(arterial blood pressure above 160/90 mmHg and below 90/60 mmHg and patients with pulse rate below 50/min and above 100/min) ,
• Patients with previously diagnosed dementia, and those who had surgical procedures lasting more than 2 hours were excluded from the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group s	Sevoflurane	Patients receiving sevoflurane
Group p	Sevoflurane	Patients receiving propofol-based total intravenous anesthesia

Primary Outcome Measures

Name	Time	Method
Group P-S	postoperative 0 1st 2nd hours	Incidence of postoperative delirium in patients receiving sevoflurane or propofol-based total intravenous anesthesia

Trial Locations

Locations (1)

Amasya University Hospital; 🇹🇷 Amasya, Turkey