Comparison of tympanic membrane grafting medial or lateral to malleus handle
Phase 2
Completed
- Conditions
- Success of surgery.Chronic suppurative otitis media NOS
- Registration Number
- IRCT201211062106N3
- Lead Sponsor
- Isfahan University of Medical Sciences, Vice Chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
Those patients with dry ear; no history of Diabetes Mellitus, autoimmune disease and smoking.
Exclusion criteria were: no compliance for follow up; beginning of active otorrhea; ear trauma and upper airway infection.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete repair of tympanic membrane, without lateralization, atelectasis, blunting or retraction pocket. Timepoint: 3 months after surgery. Method of measurement: Physical examination.
- Secondary Outcome Measures
Name Time Method Mean air-bone gap. Timepoint: 3 months after intervention. Method of measurement: Pure Tone Audiometery.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms underlying tympanic membrane grafting in chronic suppurative otitis media?
How does graft placement medial or lateral to the malleus handle affect surgical outcomes in CSOM patients?
Are there specific biomarkers that predict graft success in tympanic membrane repair for CSOM NOS?
What are the potential adverse events associated with tympanic membrane grafting in phase II trials?
How does this trial compare to standard-of-care tympanoplasty techniques for chronic suppurative otitis media?