NCT01810978已完成不适用
Efficacy of Synbiotics in Infants With Cyanotic Congenital Heart Disease
Dr. Sami Ulus Children's Hospital2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Sepsis
研究概览
简要总结
Infants with congenital heart disease have more frequent infections and exposures to antibiotics than healthy infants. The investigators hypothesized that synbiotics may reduce the rate of sepsis and necrotizing enterocolitis in infants with CHD
详细描述
Infants with congenital heart disease have more frequent infections and exposures to antibiotics than healthy infants. Probiotics may prevent pathogen colonization in infants with CHD. Therefore, the investigators hypothesized that synbiotics may reduce the rate of sepsis and necrotizing enterocolitis in infants with CHD
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 1 Day 至 3 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cyanotic congenital heart disease
- •infants >35 weeks of gestational age
- •Born at or transferred to Sami Ulus CH
排除标准
- •Congenital anomalies of the intestinal tract
结局指标
主要结局
Sepsis
时间窗: 8 weeks
次要结局
- Necrotizing enterocolitis(8 weeks)
研究者
Dilek Dilli
Assoc Prof
Dr. Sami Ulus Children's Hospital
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Probiotics in Infants With Cyanotic Congenital Heart DiseaseCyanotic Congenital Heart DiseaseNCT01018472University of California, Davis12
已完成
不适用
Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary BypassCongenital Heart DiseaseIntestinal DiseaseDysbiosisNCT06295575Nanjing Children's Hospital80
招募中
3 期
Effect of synbiotics in patients with Behcet's diseaseBehcet's diseaseIRCT20240429061594N1Tabriz University of Medical Sciences28
已完成
不适用
Effect of synbiotics in infants with atopic dermatitis up to 7 years of lifeAsthma and allergies1000170810038716NL-OMON34194Danone Research - Centre for Specialised Nutrition78
招募中
不适用
Synbiotics in Patients at RIsk fOr Preterm BirthPreterm Spontaneous Labor With Preterm DeliveryPreterm BirthMicrobial ColonizationNCT05966649Ziekenhuis Oost-Limburg402