Effect of synbiotics in infants with atopic dermatitis up to 7 years of life
Completed
- Conditions
- Asthma and allergies1000170810038716
- Registration Number
- NL-OMON34194
- Lead Sponsor
- Danone Research - Centre for Specialised Nutrition
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 78
Inclusion Criteria
- Participation to and completion of the Synbad study
- Between 5 years and 6 months and 6 years of age
- Written informed consent from parents/caregivers/legal representatives
Exclusion Criteria
Investigator's uncertainty about the willingness or ability of the family to comply with the
protocol requirements
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter of this study is the physician*s diagnosed asthma<br /><br>and controllability (GINA classification) at the age up to 7 years.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- Allergic manifestations: diagnosed by physician or by means of questionnaires<br /><br>(ISAAC derived), including severity (if available)<br /><br>- Blood analysis (Ig's, cytokines)<br /><br>- Fecal parameters (bacterial content, PH)<br /><br>- Anthropometry<br /><br>- Molecular pattern recognition by smell prints of exhaled volatile organic<br /><br>compounds (Electronic Nose®)</p><br>