Effect of Degranulation Needle on the Rate Good Embryo in IVF
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- quality of embryo
研究概览
简要总结
Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.
详细描述
Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. The participants were divided into two group. Odd-numbered days the zygotes were degranulated with the 140 microns needles. Even-numbered days the zygotes were degranulated with the 150 microns needles. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 22 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •first cyele of IVF treatment
排除标准
- •oocyte number less than 4
- •oocyte number over than 25
研究组 & 干预措施
Odd-numbered days
Once odd-numbered days the zytoges of IVF cycle were collected. The 140 microns denuding pipette was used.
干预措施: 140 microns denuding pipette (Device)
Even-numbered days
Once even-numbered days the zytoges of IVF cycle were collected. The 150 microns denuding pipette was used.
干预措施: 150 microns denuding pipette (Device)
结局指标
主要结局
quality of embryo
时间窗: one year
embryo quality assessed by good embryo rate
次要结局
- clinical outcome - clinical prengancy rate(three years)