study of immunupathogenesis of extrafacial melasma in skin of color
Not Applicable
- Conditions
- Health Condition 1: L814- Other melanin hyperpigmentation
- Registration Number
- CTRI/2023/09/057682
- Lead Sponsor
- Pigmentary Disorders Society
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age over 18 years
Clinical diagnosis of extra-facial melasma characterized by the presence of brownish hyperpigmented spots under regular illumination, with irregular borders, symmetrically distributed in body areas except the face.
Exclusion Criteria
1 History of post-inflammatory hyperpigmentation and hyperchromic contact dermatitis with symptoms such as itching, stinging, burning, or local trauma before the appearance of the lesions.
2 Pregnant women
3 Patients with contraindications for skin biopsy such as a history of keloid formation or coagulation disorders
4. Patients not giving consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To compare pathogenic mechanisms of facial and extrafacial melasma on immunohistochemical analysisTimepoint: at 1 year
- Secondary Outcome Measures
Name Time Method 2.To study the immunohistochemistry in extrafacial melasmaTimepoint: 1 year