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Efficacy and Safety of Thread Embedding Therapy for Chronic Low Back Pain: A randomized, controlled, assessor-blinded, multicenter clinical trial

Not Applicable
Recruiting
Conditions
Diseases of the musculo-skeletal system and connective tissue
Registration Number
KCT0002666
Lead Sponsor
Kyung Hee University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
38
Inclusion Criteria

1. Male and female subjects aged from 19 to 65
2. Low Back Pain which lasted more than 3 months is main chief complaint
3. Pain and discomfort due to low back pain is greater than 4 on the 10-cm visual analog scale (VAS) for one week before the enrollment
4. Participants who signed the agreed consent to follow instructions voluntarily after listening to the detailed explanation of this clinical trial

Exclusion Criteria

1. Persons who have history of hypersensitive reactions of embedding therapy or acupuncture treatment
2. Those who have abnormalities in the lower neurological examination
3. Those who have cauda equine syndrome or neurological symptoms of sensory or motor paralysis which need surgical treatments.
4. Those who have history of the spinal surgery or plans for surgery during the clinical trial period
5. Neuromuscular scoliosis or neurodegenerative disease
6. Those with diagnosed diseases which can be the possible cause of back pain: vertebral fracture, inflammatory spondylitis, spinal infection, malignant tumor, etc.
7. Female subects who are pregnant, or are brease-feeding or has plans for pregnancy plan, or does not consent to the choice of appropriate method of contraception.
8. Those who received acupuncture, medication, physical therapy, or manipulation therapy related to back pain within the last 2 weeks
9. Those taking anticoagulants
10. Those who have more severe pain in another area other than the low back area
11. If clinical trial investigators judges that it is inappropriate for the subject to be enrolled for a fair reason

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
pain scores (VAS)
Secondary Outcome Measures
NameTimeMethod
Change of pain scores (VAS);the clinical relevances (MCID, reduction ratio of 2 points or more on VAS compared to the 0 week (V1);the clinical relevances (MCID, reduction ratio of VAS 30% or more compared to the 0 week (V1);the clinical relevances (MCID, reduction ratio of VAS 50% or more compared to the 0 week (V1);Change of Roland and Morris Disability Questionnaire (RMDQ) scores;Change of EuroQol (EQ-5D) scores; Change of Patient Global Impression of Change;Cost-benefit analysis and cost-effectiveness analysis between the two groups.
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