A Multi-center Observational Clinical Study of Screening of Non-small-cell Lung Cancer With Bone Metastasis and Efficacy and Safety of Those Receiving Bisphosphonates

Sun Yat-sen University1 site in 1 country432 target enrollmentAugust 2008

ConditionsNon-small Cell Lung Cancer Bone Metastases

Interventionsbisphosphates

Drugsbisphosphates

Overview

Phase: Phase 4
Intervention: bisphosphates
Conditions: Non-small Cell Lung Cancer
Sponsor: Sun Yat-sen University
Enrollment: 432
Locations: 1
Primary Endpoint: Skeleton-related event
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

A multicenter Prospective Study to assess the screening methods, parameter of NTX and the efficacy and safety of zoledronic acid treatment in addition to anti-tumor therapy in patients of non-small cell cancer with bone metastasis in china.

Registry

clinicaltrials.gov

Start Date

August 2008

End Date

May 2012

Last Updated

12 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Sun Yat-sen University

Responsible Party

Principal Investigator

Li Zhang

Profressor

Sun Yat-sen University

Eligibility Criteria

Inclusion Criteria

•Age \>18, either sex
•Histologically confirmed non-small cell cancer
•One bone metastasis at least confirmed by image(X ray,CT or others)
•Without receiving zoledronic acid
•Life expectancy \> 6 M

Exclusion Criteria

•Women who are pregnant or in lactation
•Patients with hyperostosis
•with brain metastasis(exception of those without symptom or with Metastasis Lesions under controlled
•Previous or current treatment with any other bisphosphonates, bone- protecting, cytotoxic or targeted therapy
•Severe co-morbidity of any type that may interfere with assessment of the patient for the study -