Efficacy of Cantharidin in Molluscum Contagiosum: A Randomized, Blinded, Placebo-Controlled Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 29
- 试验地点
- 1
- 主要终点
- Patients Experiencing Complete Clearance of All Molluscum Lesions.
研究概览
简要总结
The University of North Carolina Department of Dermatology is conducting a clinical trial to evaluate a drug called cantharidin in the treatment of molluscum contagiosum. Molluscum is a common dermatologic disorder caused by a poxvirus. Molluscum typically presents with many flesh-colored bumps on the skin. It goes away on its own, though can last several months to several years. Cantharidin is a topical medicine which is applied at the clinic visit. It is well tolerated by the majority of children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 5 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Anyone aged 5-10 years with the clinical diagnosis of molluscum contagiosum.
排除标准
- •Anyone with immunosuppression including HIV or previous organ transplantation.
- •Anyone taking immunosuppressive medications.
- •Anyone who has previously received treatment with cantharidin.
- •Any female who has had her first menstrual period.
研究组 & 干预措施
I
Subjects in this group will have topical application of cantharidin's vehicle at each visit.
干预措施: cantharidin's vehicle (Drug)
II
Subjects in this group will have topical application of cantharidin at each visit.
干预措施: Cantharidin 0.7% (Drug)
结局指标
主要结局
Patients Experiencing Complete Clearance of All Molluscum Lesions.
时间窗: Baseline compared to 8 weeks (5 visits)
次要结局
- Mean Change in Each Group Measured by Lesion Count.(Baseline compared to 8 weeks (5 visits))