Defining Volume Status with Extracellular Water Measurement in Patients with Intracranial Hemorrhage

Not yet recruiting

• Conditions: Intracranial Hemorrhages

• Registration Number: NCT06590688
• Lead Sponsor: Uppsala University

Brief Summary

The goal of this observational study is to learn about the influence of extracellular water on volume status in adult patients with intracranial hemorrhage presenting with hemodynamic instability. The main question it aims to answer is:

• Can measurement of extracellular water contribute to the description of hemodynamic instability in adult patients with intracranial hemorrhage. Patients with intracranial hemorrhage admitted to intensive care will receive standard care with the addition of measurement of extracellular water.

Detailed Description

Adult patients with intracranial hemorrhage admitted to ICU will be recruited. During the first five days after inclusion blood samples and extended non-invasive monitoring, including monitoring of the microcirculation (CytoCam) and measurement of extracellular water (dielectronic constant), will be added to routine care and monitoring.

Study Timeline

• Study First Submitted: 2024-07-18
• Status Verified: 2024-09
• Study First Submitted QC: 2024-09-09
• Last Update Submitted: 2024-09-09
• Study First Posted: 2024-09-11
• Last Update Posted: 2024-09-11
• Study Start: 2024-09-23
• Primary Completion: 2026-09
• Study Completion: 2026-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Adults with intracranial hemorrhage admitted to ICU.

Exclusion Criteria

• Pregnancy, palliative care.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Extracellular water for volume status characterization in patients with intracranial hemorrhage.	7 days	Can measurement of extracellular water (MoistureMeterD, Delfin Technologies Ltd, Kuopio, Finland) contribute to the description of hemodynamic instability in adult patients with intracranial hemorrhage during the first five days?