To compare the onset and recovery time of minimal flow sevoflurane and desflurane anaesthesia.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/10/046418
• Lead Sponsor: Maulana Azad Medical College

Brief Summary

Sevoflurane and Desflurane are the two most common gases used in minimal flow anaesthesia.

The aim of this study is to evaluate and compare the onset and recovery characteristics in minimal flow sevoflurane and desflurane anaesthesia.

Patients will be divided into two groups Group D and Group S receiving Desflurane and sevoflurane respectively by computer generated sequence. Standard anaesthesia induction protocol will be followed,and airway will be secured using endotracheal tube or supraglottic device, following which inhalation agent will be started according to the allotted group.

Primary objective is to see time to achieve MAC of 0.9 and eye opening following vaporizer closure whereas secondary objective is to see the hemodyamic effects, BIS value  along with carbon footprints of minimal flow sevoflurane and Desflurane anaesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-15
• Last Update Posted: 2022-11-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Age 18-65 years 2.
• ASA physical status 1 and 2 3.
• Duration of surgery >1 hour.

Exclusion Criteria

• History of hepatic,renal,or cardiovascular disease 2.Patient with chronic obstructive pulmonary disease 3.
• Pregnant patient 4.Obesity (BMI >30kg/m2).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Onset time	1.time in seconds after intubation to acheive MAC of 0.9 | 2.time in seconds after vaporizer closure to eye opening
2.Recovery time	1.time in seconds after intubation to acheive MAC of 0.9 | 2.time in seconds after vaporizer closure to eye opening

Secondary Outcome Measures

Name	Time	Method
1.systolic blood pressure, diastolic blood pressure, heart rate and Spo2	2.Bispectral index

Trial Locations

Locations (1)

Maulana Azad Medical College and associated hospitals; 🇮🇳 Central, DELHI, India

Maulana Azad Medical College and associated hospitals

🇮🇳Central, DELHI, India

Megha Ranjan

Principal investigator

9315937836

meghakmr5@gmail.com