Comparative Study of Training Modality After Myocardial Infarction; Standard Care Rehabilitation Training or Interval Treadmill Training
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 89
- Locations
- 3
- Primary Endpoint
- change in maximal oxygen consumption
Study Overview
Brief Summary
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period.
Detailed Description
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period.
Primary outcome: Maximal oxygen consumption Secondary outcomes: Blood values (for endothelial function, blood lipids, etc), flow mediated dilatation, quality of life (SF 36 and MacNew), weight, BMI, heart rate fall 1 minute after stopping the maximal treadmill test.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Myocardial infarction 2-12 weeks ago
Exclusion Criteria
- •Heart failure
- •limitations to walking on a treadmill
- •failure to reach a maximal pre-test(> NYHA class II)
- •uncontrolled hypertension
- •pregnancy
- •kidney failure (creatinin > 140)
- •drug abuse
- •left ventricle EF < 30%
Arms & Interventions
1
Standard exercise training rehabilitation at the hospital
Intervention: Exercise training (Behavioral)
2
Interval exercise training on treadmills, with high intensity
Intervention: Exercise training (Behavioral)
Outcomes
Primary Outcomes
change in maximal oxygen consumption
Time Frame: baseline, after intervention and at 6 months
At baseline, following intervention and at 6 months after the intervention. An additional follow-up test will be conducted in all patients who want to participate during 2009.
Secondary Outcomes
- quality of life(baseline, after intervention and at 6 months)
- flow mediated dilatation(baseline, after intervention and at 6 months)
- echocardiography(baseline, after intervention and at 6 months)
- blood markers(baseline, after intervention and at 6 months)