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临床试验/NCT06376071
NCT06376071尚未招募不适用

Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis

Assiut University0 个研究点目标入组 76 人开始时间: 2024年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
76
主要终点
Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhinosinusitis

研究概览

简要总结

This study aims to assess Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhino sinusitis regarding::

  1. anatomical variations and correlate radiological finding with intraoperative finding.
  2. other associated factors like demographic ,environmental, immunological and climatic risk factors .

详细描述

Introduction Allergic fungal rhinosinusitis (AFRS) is a subtype of CRS with nasal polyposis (CRSwNP) that is characterized by eosinophilic mucin within expanded sinus cavities and immunoglobulin E (IgE)-mediated type 1 hypersensitivity to fungal elements. This noninvasive disease process typically affects immunocompetent, younger patients in geographic regions with warm temperatures and high humidity, which facilitate fungal proliferation.

AFRS has a worldwide distribution pattern with varying prevalence. AFRS is presented in variable rates in different climatic, socioeconomic, and geographic factors. The disease prevalence showed predilection toward climatic factors

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhinosinusitis

时间窗: baseline

analysis of the risk factors of unilateral versus bilateral allergic fungal rhinosinusitis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Al khater nosir sayed

Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhinosinusitis

Assiut University

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