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Clinical Trials/CTRI/2026/03/106408
CTRI/2026/03/106408
Not yet recruiting
Not Applicable

Comparison of Skeletal and Dentoalveolar Changes After Maxillary Expansion Using MARPE and Hybrid Hyrax Appliance in the Maxilomandibular Complex

Sri Hasanamba Dental College and Hospital.1 site in 1 country18 target enrollmentStarted: March 27, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Sri Hasanamba Dental College and Hospital.
Enrollment
18
Locations
1
Primary Endpoint
The following parameters will be assessed using CBCT images:

Overview

Brief Summary

This study aims to compare the skeletal and dentoalveolar changes produced by two maxillary expansion appliances namely MARPE and Hybrid Hyrax in patients with transverse maxillary constriction. The study includes eighteen participants aged between twelve and seventeen years who are undergoing fixed orthodontic treatment. Participants are divided into two groups based on the type of expander used. Three dimensional CBCT images are taken before maxillary expansion and three months after completion of expansion following the retention period. Skeletal alveolar and dental changes in the maxilla and mandible are evaluated in coronal and axial planes using CBCT measurements. The results of this study will help in understanding the pattern and magnitude of changes produced by MARPE and Hybrid Hyrax appliances and assist in selecting the appropriate expansion method in adolescent patients.

Study Design

Study Type
Interventional
Allocation
Na
Masking
Outcome Assessor Blinded

Eligibility Criteria

Ages
17.00 Year(s) to 25.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Subjects aged between 17 to 25 years Subject with maxillary skeletal constriction value less than 0.8 according to YTI index Subjects with good oral hygiene.

Exclusion Criteria

  • Patients with a previous history of orthodontic treatment Patients with any syndromes or systemic diseases The presence of any signs and symptoms of periodontal disease Previous history of any surgical procedure in the maxilla Patients with Palatal tori Patients with impacted maxillary first premolars and molars Patients with temporomandibular disorders.

Outcomes

Primary Outcomes

The following parameters will be assessed using CBCT images:

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Maxillary skeletal expansion

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Maxillary alveolar expansion

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Mandibular alveolar expansion

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Maxillary dental expansion

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Mandibular dental expansion

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Anteroposterior changes in the maxilla and mandible

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Changes in skeletal, alveolar, and dental dimensions in the coronal plane

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

These parameters will be evaluated to compare the effects of MARPE and Hybrid Hyrax expanders.

Time Frame: Time Points of Assessment | CBCT measurements will be recorded at two time points: | T0 (Baseline): Before maxillary expansion. | T1 (Post-treatment): 3 months after completion of maxillary expansion

Secondary Outcomes

  • Change in anteroposterior (axial plane) position of the maxilla and mandible following maxillary expansion using MARPE and Hybrid Hyrax appliances, assessed on CBCT.(T0: Pre-expansion)
  • Change in mandibular transverse width (skeletal, alveolar, and dental levels) following maxillary expansion using MARPE and Hybrid Hyrax appliances, assessed using CBCT.(T0: Pre-expansion)
  • Comparison of pattern of expansion (skeletal versus dentoalveolar contribution) between MARPE and Hybrid Hyrax appliances using CBCT measurements.(T0: Pre-expansion)

Investigators

Sponsor
Sri Hasanamba Dental College and Hospital.
Sponsor Class
Private hospital/clinic
Responsible Party
Principal Investigator
Principal Investigator

Dr Albin Joji

SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL

Study Sites (1)

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